Cefuroxime, sold under the brand name Zinacef among others, is a second-generation cephalosporin [3] antibiotic used to treat and prevent a number of bacterial infections. [4] These include pneumonia, meningitis, otitis media, sepsis, urinary tract infections, and Lyme disease. [5] It is used by mouth or by injection into a vein or muscle. [5]

Apr 12, 2023 · Second generation cephalosporins were the second generation of cephalosporins to be developed. Cephalosporins are a large group of antibiotics derived from the mold Acremonium (previously called Cephalosporium).

Feb 17, 2024 · Cephalosporins are β-lactam antimicrobials used to manage various infections caused by both gram-positive and gram-negative bacteria. Cephalosporins are categorized into 5 generations based on their spectrum of coverage against gram-positive and gram-negative bacteria and their temporal discovery.

Jan 11, 2024 · Cefuroxime belongs to the second generation of cephalosporin antibiotics and is classified as a β-lactam agent. Cefuroxime was approved by the U.S. Food and Drug Administration (FDA) in December 1987, and it exhibits broad-spectrum activity against both gram-positive and gram-negative organisms, making the drug effective for treating a wide ...

Feb 12, 2024 · Cefuroxime is a second-generation cephalosporin-type antibiotic that may be used for the treatment of bacterial infections caused by susceptible strains of bacteria.

Jan 31, 2025 · Ceftin is a cephalosporin (SEF a low spor in) antibiotic. It works by fighting bacteria in your body. Ceftin is used to treat bacterial infections of the ear, nose, throat, lungs, skin, bones, joints, bladder, or kidneys. Cefuroxime is also used to …

Jan 28, 2019 · Third-generation cephalosporins are effective against many Gram-negative bacteria and bacteria that haven’t responded to first- or second-generation cephalosporins.

Cefuroxime axetil is a second generation cephalosporin that, like penicillins antibiotics, contains a β-lactam ring structure. Cephalosporins work as bactericidal antibiotics; that by binding to penicillin-binding proteins (PBPs), inhibit the last step of the bacterial cell wall synthesis.

Oct 11, 2023 · Cephalosporins are divided into five generations. However, different cephalosporins in the same generation are sometimes chemically unrelated and have different …

Cephalosporins are β-lactam antibiotics, which are grouped into four generations according to their antibiotic spectrum of activity (Simon and Stille, 1997). The first generation has mainly gram-positive activity. The second and third generation has more gram-negative activity with decreased activity against gram-positive bacteria.