Cyclin-dependent kinase - Wikipedia
Cyclin-dependent kinases (CDKs) are a predominant group of serine/threonine protein kinases involved in the regulation of the cell cycle and its progression, ensuring the integrity and functionality of cellular machinery.
Cyclin-dependent kinases | Genome Biology | Full Text
Jun 30, 2014 · Cyclin-dependent kinases (CDKs) are protein kinases characterized by needing a separate subunit - a cyclin - that provides domains essential for enzymatic activity. CDKs play important roles in the control of cell division and modulate transcription in response to several extra- and intracellular cues.
CDK | Learn Science at Scitable - Nature
CDKs are a family of multifunctional enzymes that can modify various protein substrates involved in cell cycle progression. Specifically, CDKs phosphorylate their substrates by transferring...
Cyclin-dependent kinases - PubMed
Cyclin-dependent kinases (CDKs) are protein kinases characterized by needing a separate subunit - a cyclin - that provides domains essential for enzymatic activity.
Cyclin-dependent kinases: a family portrait | Nature Cell Biology
Cyclin-dependent kinases (CDKs) are protein kinases involved in critical cellular processes, such as cell cycle or transcription, whose activity requires association with specific cyclin...
Targeting CDK1 in cancer: mechanisms and implications
Jun 13, 2023 · Cyclin dependent kinases (CDKs) are serine/threonine kinases that are proposed as promising candidate targets for cancer treatment. These proteins complexed with cyclins play a critical role...
Cyclin-dependent kinases: a family portrait - PMC
Cyclin-dependent kinases (CDKs) are protein kinases involved in critical cellular processes, such as cell cycle or transcription, whose activity requires association with specific cyclin subunits.
Cyclin-Dependent Kinase - an overview | ScienceDirect Topics
Sep 16, 2018 · Cyclin-dependent kinase 13 (CDK13) is also called cell division cycle 2-like protein kinase 5 (CDC2L5) and cholinesterase-related cell division controller (CHED). It was first identified in a phage λgt10 cDNA library from human glioblastoma and was shown to be expressed in fetal brain, liver, and muscle, and adult whole brain, hippocampus, and ...
Cyclin-Dependent Kinases (CDK) and Their Role in Diseases ... - PubMed
Mar 13, 2021 · Protein Kinase Inhibitors. Cyclin-Dependent Kinases. Cyclin-dependent kinases (CDKs) are involved in many crucial processes, such as cell cycle and transcription, as well as communication, metabolism, and apoptosis. The kinases are organized in a pathway to ensure that, during cell division, each cell accurately replicates its DNA, and ensure ...
Cyclin‐dependent kinases: Masters of the eukaryotic universe
Cyclin‐dependent kinases (CDKs) are a conserved eukaryotic family of heterodimeric serine/threonine protein kinases, whose catalytic activity is entirely dependent on association with a specialized regulatory cyclin subunit and the phosphorylation status of the CDK activating domain, the T‐loop (Brown et al., 1999; Malumbres, 2014; Pines, 1995; ...