This cancer is the biggest problem of all, so we decided to use the A549 cell line for our research [33]. Therefore, three new coordination compounds were designed, synthesized, and investigated. The cytotoxic activity of the synthesized complexes was studied in vitro towards lung carcinoma cell line.
Learn more:This cancer is the biggest problem of all, so we decided to use the A549 cell line for our research [33]. Therefore, three new coordination compounds were designed, synthesized, and investigated. The cytotoxic activity of the synthesized complexes was studied in vitro towards lung carcinoma cell line.
pmc.ncbi.nlm.nih.gov/articles/PMC8950742/A key problem in current cancer therapy is the lack of neoplastic cell specificity. It leads to cytotoxicity against tumors as well as to normal cells and, consequently, causes drug resistance. The use of nanoparticles may be a solution in this case [27, 28, 29, 30].
www.mdpi.com/1422-0067/23/6/2980The thermal behavior of investigated compounds was studied in the temperature range 25-800 °C. All compounds are stable at room temperature. The complexes decompose in several stages. Magnetic studies revealed strong antiferromagnetic interaction. Their cytotoxic activity against A549 lung cancer cells have been studied with promising results.
pubmed.ncbi.nlm.nih.gov/35328401/The combination of erlotinib and cabozantinib demonstrated significant apoptotic activity against human lung cancer cell-lines A549 in cell culture and suppressed the growth of xenograft tumors in athymic nude mice.
www.sciencedirect.com/science/article/pii/S131901…Abstract Objective: In this study, we investigated the antitumor activity of interleukin (IL)-18 on A549 human lung cancer cell line and evaluated the potential of IL-18 therapy in lung cancer.
pubmed.ncbi.nlm.nih.gov/31939449/Antitumor Activity against A549 Cancer Cells of Three Novel …
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