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  1. ACTH - Side effects

    Common side effects

    • Hypercortisolism
    • Mood changes
    • Hypertension
    • Hirsutism
    • Irritability
    • Behavioral disorders
    • Diarrhea
    • Increased appetite
    • Acne vulgaris
    • Infection
    • Body fluid retention
    • Weight gain
    • Hypothalamic-pituitary insufficiency
    • Hypocalcemia
    • Hypernatremia
    • Hypokalemia
    • Hyperglycemia
    • Constipation
    • Nasal congestion
    • Skin rash

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    Precautions

    • Before use, important to read the Medication Guide
    • Learn and use proper injection technique
    • MD may need to reduce the dose before you stop it.
    • Reduce or limit drinking alcohol
    • May increase blood sugar
    • Ask MD about lifestyle changes for bone health.
    • Call Dr if you have black stools or stomach pain
    • Refrigerate and protect from light

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    Warnings

    • For drops products : Take this medication at least 1 hour before or 1 hour after magnesium or aluminum containing antacids, iron, or vitamins/minerals.
    • For lozenge products : Allow medication to dissolve slowly in the mouth. Do not chew or swallow whole.
    • For tablet, chewable products : Chew this medication before swallowing.

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    How does ACTH work?
    ACTH tells your adrenal glands, two small glands that sit above your kidneys, to make another hormone called cortisol. Cortisol affects almost every organ and tissue in your body. It helps your body: Because ACTH controls how much cortisol you make, ACTH testing is usually done with a blood test to measure your cortisol levels.
    medlineplus.gov

    Interactions

    Products that may interact with this drug include:

    • Other vitamin/nutritional supplements

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    Overview

    This medication is used to treat a certain type of seizure in children (infantile spasms). This medication is also used to treat conditions such as multiple sclerosis, arthritis, lupus, eye conditions, skin/kidney/lung diseases, and immune system disorders.

    Status: Discontinued

    May Treat: Iridocyclitis · Stevens-Johnson syndrome · Acute exacerbation of multiple sclerosis · Ankylosing spondylitis · Chorioretinitis and more

    Alternate Brand Names: Acthar

    Drug Class: Adrenocorticotrophic Hormones

    Availability: Prescription sometimes needed

    Pregnancy: Consult a doctor before using

    Lactation: Consult a doctor before using

    Alcohol: Limit intake while taking this medication

    Driving: May cause drowsiness or dizziness. Use caution

    Manufacturer: FOREST PHARMACE

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    Source: First Databank. For informational purposes only. Consult a medical professional for advice.
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    Table of Contents
    Side effects
    Precautions
    Warnings
    How does ACTH work?
    Interactions
    Ask an expert
    Overview
     
  1. ACTH is a hormone produced by the pituitary gland in the brain. This medicine is injected into the thigh muscle to reduce infantile spasms. Infantile spasms (IS) is a type of epilepsy that usually occurs in babies and is often associated with development problems.
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    What is ACTH Therapy (Corticotropin/ACTHAR Gel) for Infantile Sp…

    www.med.umich.edu/1libr/Pharmacy/ACTHInjections.pdf
    www.med.umich.edu/1libr/Pharmacy/ACTHInjections.pdf
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  2. People also ask
    Is Acthar gel available in a single-dose injector or multi-dose vial?
    Acthar Gel is available in the single-dose pre-filled SelfJect TM injector or in multi-dose vials. Talk with your healthcare provider about which option may be right for you. Already have an Acthar Gel prescription? Learn more about the resources available to you below.

    Acthar® Gel (repository corticotropin injection) for Patients & Caregivers

    acthar.com
    What is Acthar gel (corticotropin)?
    Acthar Gel (corticotropin) is thought to lower inflammation and the activity of the immune system by triggering the release of steroid hormones (e.g., cortisol) and binding to certain proteins. Are you looking for information on Cortrophin Gel (corticotropin) instead? What are the side effects of Acthar Gel (corticotropin)?

    Acthar Gel (Corticotropin): Uses, Side Effects, Alternatives ... - GoodRx

    goodrx.com
    How does ACTH work?
    ACTH tells your adrenal glands, two small glands that sit above your kidneys, to make another hormone called cortisol. Cortisol affects almost every organ and tissue in your body. It helps your body: Because ACTH controls how much cortisol you make, ACTH testing is usually done with a blood test to measure your cortisol levels.

    Adrenocorticotropic Hormone (ACTH): MedlinePlus Medical Test

    medlineplus.gov
    How does Acthar gel release endogenous ACTH?
    Acthar Gel stimulates the release of endogenous ACTH under the influence of the nervous system via the regulatory hormone released from the hypothalamus. This release is also influenced by a negative corticosteroid feedback mechanism. Elevated plasma cortisol suppresses ACTH release. Acthar Gel is also reported to bind to melanocortin receptors.

    H.P. Acthar Gel: Package Insert - Drugs.com

    drugs.com
    How do I keep track of my Acthar gel (corticotropin) injections?
    Use the calendar in the Acthar Gel treatment journal to record the details of your Acthar Gel (corticotropin) injections. After injecting the medication, throw away the Acthar Gel (corticotropin) pen in a sharps container or something made of heavy-duty plastic, such as an empty milk carton or laundry detergent bottle.

    Acthar Gel (Corticotropin): Uses, Side Effects, Alternatives ... - GoodRx

    goodrx.com
    Is Acthar gel a sterile preparation?
    Acthar Gel is a sterile preparation supplied as a 16% gelatin to ensure a prolonged release after intramuscular or subcutaneous injection. It also contains 0.5% phenol, not more than 0.1% cysteine (added), sodium hydroxide and/or acetic acid to adjust pH and water for injection. (12. H.P. Acthar Gel - Clinical Pharmacology)

    H.P. Acthar Gel: Package Insert - Drugs.com

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  3. WebMD
    https://www.webmd.com › drugs › acth-injection › details

    ACTH 80 Unit/Ml Injection Gel - Uses, Side Effects, and More

  4. Acthar Gel
    https://acthar.com

    Acthar® Gel (repository corticotropin injection) for Patients

  5. Drugs.com
    https://www.drugs.com › pro › h-p-acthar-gel.html

    H.P. Acthar Gel: Package Insert / Prescribing Info - Drugs.com

  6. Purified Cortrophin® Gel
    https://cortrophin.com

    Purified Cortrophin® Gel (repository corticotropin …

    Cortrophin Gel is an ACTH injection therapy approved for the following conditions: Acute attacks or flares of multiple sclerosis. Reduction of protein in the urine of people with nephrotic syndrome of the idiopathic type (unknown …

  7. Acthar Gel
    https://www.actharhcp.com › administration

    Administration | Acthar® Gel (repository corticotropin injection)

  8. MedlinePlus
    https://medlineplus.gov › lab-tests › adre…

    Adrenocorticotropic Hormone (ACTH): MedlinePlus …

    An adrenocorticotropic hormone (ACTH) test measures the amount of ACTH in your blood. It can help find the cause of abnormal cortisol levels. Learn more.

  9. Survival Flight
    https://www.med.umich.edu › Pharmacy › ACTHInjections.pdf
    [PDF]

    What is ACTH Therapy (Corticotropin/ACTHAR Gel) for …

  10. GoodRx
    https://www.goodrx.com › acthar-gel › what-is

    Acthar Gel (Corticotropin): Uses, Side Effects, Alternatives

  11. Acthar Gel
    https://www.acthar.com › Static › pdf › Acthar-PI.pdf
    [PDF]

    Acthar Gel

  12. DailyMed
    https://dailymed.nlm.nih.gov › dailyme…

    Cortrosyn (cosyntropin) 0.25 mg Injection, USP 1ml Vial …

    CORTROSYN™ (cosyntropin) for Injection is a sterile lyophilized powder in vials containing 0.25 mg of CORTROSYN™ and 10 mg of mannitol to be reconstituted with 1 mL of 0.9% Sodium Chloride Injection, USP. Administration is by …