Contraction alkalosis | Student Doctor Network
WEBJul 1, 2012 · Sodium is reabsorbed in the collecting tubule, drawing water with it AND... also in the collecting duct, lots of acid is lost (under direction of aldo), and a lot of base gets absorbed. The idea is dehydration = high aldo = acid secretion and bicarb retention. The "contraction" part of contraction alkalosis is "contraction" of the vascular volume.
contraction alkalosis | Student Doctor Network
WEBMar 16, 2007 · In the context of vomiting and resultant volume contraction the mechanism for met alkalosis isn't just losing stomach acid through vomiting. Along with H+ you also lose Chloride (in the form of HCl) when vomiting. volume contaction then of course causes the kidneys to reabsorb Na, and thus water, for volume repletion.
contraction alkalosis? | Student Doctor Network
WEBNov 26, 2013 · Hi metabolic alkalosis can be grouped in 4-5 broad groups. GI H+ loss; Renal H+ loss; H+ shift inside cell; Administration of "HCO3-" and contraction alkalosis; If you lose a big volume of bicarbonate-free fluid and you have a relatively constant amount of extracellular bicarbonate, contraction alkalosis occurs. In CF you loose a solution of ...
Angiotensin II and HCO3- - Student Doctor Network Communities
WEBNov 7, 2010 · It isn't that HCO3- reabsorption causes contraction alkalosis. Instead, ECF volume contraction causes metabolic alkalosis. 1. ECF volume contraction (dehydration from vomiting, for example) stimulates isosmotic reabsorption in the proximal tubule (because the body wants to increase volume) as well as stimulates HCO3 reabsorption; …
Chloride responsiveness and metabolic alkalosis
WEBMar 7, 2010 · In metabolic alkalosis, there's excess HCO3-. Now, if there's adequate Cl- in the urine, then it is possible to absorb that Cl- and excrete HCO3- in return. Indeed, if HCO3- excess occurred as a result of volume contraction (like you'd see in loop diuretics), then giving saline to such a patient would result Cl- to be filtered in the urine ...
diuretics and metabolic alkalosis | Student Doctor Network
WEBJun 10, 2009 · Hence, you get Met Alkalosis. 1,) Low volume causes an increase in aldosterone. Aldosterone's effect on the intercalated cell is to pump out an H+ = increase pH. 2.) Low K+ causes a transcellular shift for hydrogen ion. K+ leaves cell and H+ enters the cell = decrease plasma H+ = increase pH. 3.
Urinary chloride | Student Doctor Network
WEBAug 14, 2012 · Jul 2, 2013. #1. Couple questions about importance of urinary chloride in a couple different things. (1) In Conn syndrome, UW QID 956 lists urinary chloride as being increased, but it should in fact be decreased, correct? (2) When referring to saline-responsive and saline-resistant metabolic alkalosis, this is more or less contraction …
Vomiting Kidney Metabolic Alkalosis Question - Student Doctor …
WEBDec 1, 2010 · The other big thing driving contraction alkalosis is AT2 promoting Na+/H+ exchange in the proximal tubule, which leads to more bicarb reabsorption. I only mention this because for the longest time I was confused about the mechanism for contraction alkalosis, some sources say it's Aldo at the CT and others AT2 at the PCT.
Hypokalemia and Alkalosis? | Student Doctor Network
WEBApr 5, 2012 · In Conn's, as serum potassium ebbs, the principal cell basolateral Na+/K+-ATPase will begin secreting protons instead of K+, producing acidic urine, despite the alkalosis. This is still "paradoxical." The intercalated cell proton-K+ antiporter is less relevant. The "classic" paradoxical aciduria is seen with contraction alkalosis (e.g. …
USMLE Cystic Fibrosis: Transepithelial Potential Difference
WEBApr 29, 2011 · I might be wrong but I think it's something like this: Excessive loss of fluid because Cl- in sweat cannot be reabsorbed (so H2O and Na+ follow it) ==> renin ==> angiotensin II ==> increased Na+/H+ exchange at PCT which leads to increased bicarbonate reabsorption* ==> alkalosis *"Increases in angiotensin II cause increased …
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