BRCA Gene Changes: Cancer Risk and Genetic Testing
A positive test result indicates that a person has a harmful change in BRCA1 or BRCA2 (these are typically called “pathogenic” or “likely pathogenic” variants on laboratory test reports) and has …
BRCA1 and BRCA2 (PDQ®) - NCI - National Cancer Institute
Evidence-based, expert-reviewed summary about the BRCA1 and BRCA2 genes and hereditary breast and ovarian cancer. This summary also contains information about the cancer risks …
Mutaciones en el gen BRCA: el riesgo de cáncer y las pruebas …
Hoja informativa sobre los genes BRCA1 y BRCA2, qué hacer si la prueba de una persona indica que tiene cambios en uno de estos genes y las consecuencias de las pruebas genéticas.
Discovery – BRCA Connection to Breast and Ovarian Cancer
NCI-funded research helped identify inherited BRCA1 and BRCA2 genetic mutations and their connection to breast and ovarian cancer. From this research, a screening test was also …
MRI, Surgery Reduce Cancer Deaths in Women with BRCA Changes
Apr 15, 2024 · For women with inherited harmful changes in BRCA genes, MRI surveillance and salpingo-oophorectomy can modestly reduce their risk of dying from breast and ovarian …
Cancer Risk for Women Carrying BRCA Mutations - NCI
Jul 12, 2017 · Women who know they have inherited a harmful BRCA1 or BRCA2 mutation can take steps to reduce their risk of breast and ovarian cancer. But any preventive …
Genetic Testing Fact Sheet - NCI - National Cancer Institute
Clinical practice guidelines recommend genetic testing for anyone diagnosed with triple-negative breast cancer, ovarian cancer, pancreatic cancer, colorectal cancer before age 50, metastatic …
Surgery to Reduce the Risk of Breast Cancer - National Cancer …
Risk-reducing (also called preventive or prophylactic) surgery can lower the risk of breast cancer in people who are at very high risk, such as women who carry a harmful mutation in a breast …
Oral Contraceptives (Birth Control Pills) and Cancer Risk
A reduction in ovarian cancer risk with use of oral contraceptives is also seen among women who carry a harmful mutation in the BRCA1 or BRCA2 gene (19–21). Colorectal cancer: Oral …
Individual Champion/Changemaker | Division of Cancer Prevention
Mary-Claire King, Ph.D. Discovering the Hereditary Breast Cancer Gene. Research Area: Cancer Prevention. Long before scientists completed mapping the human genome in 2003, geneticist …
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