ARL13B Gene - GeneCards | AR13B Protein | AR13B Antibody
Mar 30, 2025 · ARL13B (ARF Like GTPase 13B) is a Protein Coding gene. Diseases associated with ARL13B include Joubert Syndrome 8 and Joubert Syndrome 1 . Among its related …
Arl13b regulates ciliogenesis and the dynamic localization of Shh ...
We show Arl13b is localized to the ciliary membrane and regulates tubulin modifications and ciliary length in vitro. Significantly, we found that Smoothened is enriched in Arl13b null …
ARL13B ARF like GTPase 13B [ (human)] - National Center for ...
Feb 8, 2025 · ARL13B regulates IFT-A-mediated retrograde protein trafficking within cilia through its interaction with INPP5E. Biochemical characterization of purified mammalian ARL13B …
Arl13b-regulated cilia activities are essential for polarized radial ...
Jun 30, 2013 · We found that Arl13b, a cilia-enriched small GTPase that is mutated in Joubert syndrome, was critical for the initial formation of the polarized radial progenitor scaffold.
The Ciliary Protein Arl13b Functions Outside of the Primary Cilium …
Dec 10, 2019 · In vitro, we demonstrate that Arl13b functions autonomously in neurons for their Shh-dependent guidance response. We detect Arl13b protein in axons and growth cones, far …
ARL13B regulates Sonic hedgehog signaling from outside primary …
Mar 4, 2020 · Complete loss of Arl13b disrupts cilia architecture, protein trafficking and Sonic hedgehog signaling. To determine whether ARL13B is required within cilia, we knocked in a …
Entry - *608922 - ADP-RIBOSYLATION FACTOR-LIKE GTPase 13B; ARL13B …
Mar 18, 2025 · The ARL13B gene encodes a member of the ADP-ribosylation factor-like (ARL) family of small GTPases of the RAS superfamily. ARL13B is required for proper cilia formation …
ARL13B, a Joubert Syndrome-Associated Protein, Is Critical for
Feb 20, 2019 · Mutations in the Joubert syndrome-associated small GTPase ARL13B are linked to photoreceptor impairment and vision loss. To determine the role of ARL13B in the …
Arl13b promotes the proliferation, migration, osteogenesis, and ...
Jun 1, 2023 · Arl13b (ADP-ribosylation factor-like 13B), an atypical Arf/Arl family GTPase, was identified in genetic screening as a protein essential for maintaining the integrity of cilia and …
The guanine nucleotide exchange factor Arf-like protein 13b is ...
Arf-like protein 13b (ARL13b) is a small GTPase that functions as a guanosine nucleotide exchange factor (GEF) for ARL3-GDP. ARL13b is located exclusively in photoreceptor outer …
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