The most often studied kinases are protein kinases, which are generally subdivided into tyrosine, and serine/threonine-directed kinases. As such, kinases are key signal transduction molecules relevant ...

Rony Seger (University of Washington, Seattle): “Protein kinases were traditionally classified into two main subgroups: those that phosphorylate serine or threonine residues on their protein ...

Boston): "RAS plays a central role in receptor tyrosine kinase (RTK)-stimulated signaling pathways, including those stimulated by nerve growth factor (NGF). "This paper shows that RAS functions to ...

Protein phosphorylation is a covalent post-translational modification event that is essential for regulation and maintenance of most biological processes in eukaryotes 1. Conventionally ...

Protein tyrosine kinases and protein tyrosine phosphatases coordinate ... My lab focuses on various functional characteristics of the pseudophosphatase map kinase serine/threonine binding protein ...