As the field of oligonucleotide therapeutics continues to evolve, the integration of robust analytical tools will be ...

However, our understanding of how gradual changes in gene dosage affect molecular, cellular, and organismal traits is currently limited. To address this gap, we induced gradual changes in gene ...

Once the modified RNA oligos and DNA barcodes are release from the bead into the cell, researchers can measure their effect in each cell using a high throughput assay. He concluded by thanking ...

New therapies that are less intrusive but more lasting than current interventions promise to arrest and even reverse neurodegeneration.

The oligonucleotides market has gained significant traction in recent years due to its critical role in molecular biology, genetics, and therapeutics. Oligonucleotides, short DNA or RNA molecules, are ...

If DNA is the set of genetic instructions, RNA is what reads and translates those instructions into making the proteins our cells need. RNA editing, then, is also a type of gene therapy.

Researchers have developed a groundbreaking microscopy method that enables detailed three-dimensional (3D) RNA analysis at cellular resolution in whole intact mouse brains. The new method ...

Small molecule microarrays (SMM) offer a high-throughput, efficient method to identify potential small molecule hits against protein and RNA targets. This poster demonstrates a simple SMM drug ...