Frontiers27d
Neutrophils drive pulmonary vascular leakage in MHV-1 infection of susceptible A/J mice
During infection, myeloperoxidase and elastase protein were released in the bronchoalveolar ... In summary, our data suggests that there are inborn differences in neutrophil function and these cells ...
thorax.bmj9d
Matrix metalloproteinases in destructive pulmonary pathology
matrix metalloproteinases chronic obstructive pulmonary disease tuberculosis acute respiratory distress syndrome sarcoidosis Normal lung function requires alveolar ... in which MMP-9 deficiency ...
thorax.bmj24d
Airway inflammation in cystic fibrosis: molecular mechanisms and clinical implications
In addition, the accumulation of abnormally processed CFTR in the endoplasmic reticulum results in unfolded protein responses that ... although neutrophil elastase seems to correlate with lung ...
Medscape21d
Neutrophils and Emerging Targets for Treatment in Chronic Obstructive Pulmonary Disease
An imbalance of neutrophil elastase and its inhibitor, α 1-antitrypsin, and of matrix metalloprotease-9 and its inhibitor, tissue inhibitor of matrix metalloproteases 1 (TIMP-1), lead to severe ...
Frontiers24d
Effects of neutrophil granule proteins on sepsis-associated lymphopenia and their relationship with CD4 + T-cell pyroptosis
Clinical and immunological parameters were recorded. Levels of neutrophil granule proteins, including myeloperoxidase (MPO) and neutrophil elastase (NE), and pyroptosis factors were examined.