Topical clindamycin is a first-line treatment for a severe type of acne that happens when bacteria clog pores and triggers the immune system to respond and cause inflammation (inflammatory acne).

Clindamycin and erythromycin are both superior to placebo at decreasing acne lesion counts. Comparison of erythromycin 2% gel with clindamycin 1% solution in a 12-week, randomized, parallel-group ...

Given the moderate severity of the patient's acne, the most appropriate ... with either topical clindamycin or erythromycin. The combination product of BP/erythromycin gel must be reconstituted ...