A 46-year-old man was evaluated in the rheumatology clinic because of joint pain and swelling. The examination was notable ...

Benralizumab is an eosinophil-depleting anti–interleukin-5 receptor α monoclonal antibody. The efficacy and safety of benralizumab in patients with eosinophilic esophagitis are unclear.

Dupilumab is a human monoclonal antibody that blocks interleukin-4 and interleukin-13 pathways and has shown efficacy in five different atopic diseases marked by type 2 inflammation, including ...

Care of patients with systemic immunoglobulin light chain (AL) amyloidosis has undergone transformative changes, leading to marked, steady progress in outcomes for patients over the past four decades.

Overall, 1074 patients underwent randomization (429 to amivantamab–lazertinib, 429 to osimertinib, and 216 to lazertinib). The median progression-free survival was significantly longer in the ...

Immune thrombocytopenia (ITP) is an autoimmune disease characterized by autoantibody-mediated platelet destruction. Treatment with CM313, a novel anti-CD38 monoclonal antibody, can result in ...

Supported in part by the Norwegian Dementia Genetics Network (DemGen), a grant (REC2018/915) from the HUSK study, a grant (REC2016/1226) from the MoBa study, grants (344121 to Drs. Andreassen and ...

Tandem duplication in UBTF is associated with a resistant form of AML. A menin inhibitor induced a short-lived response. Resistance was associated with mutations at the drug-binding site in MEN1 ...

Eosinophilic esophagitis is a chronic, allergic disease associated with type 2 helper T cell (Th2) inflammation that has increased rapidly in incidence and prevalence. 1 Symptoms of eosinophilic ...

Dr. Hayden S. Andrews (Medicine): A 73-year-old man was admitted to this hospital because of recurrent fever. The patient had been in his usual state of health until 22 months before the current ...

Obstructive sleep apnea is one of the most common respiratory disorders worldwide. Persons with obstructive sleep apnea can have loud snoring that is detrimental to social relationships and have ...