The contribution of Th17 cells in acute graft-versus-host disease (aGVHD) has been demonstrated in aGVHD mouse models ... The non-GVHD controls were asymptomatic allo-SCT patients.

Finally, using a mouse model of graft-versus-host disease (GVHD) and MSCs from mice deficient in iNOS or the IFNγ receptor 1 chain, the authors showed that cytokine-induced nitric-oxide ...