To overcome these barriers, many siRNA delivery systems have been developed. Among these, lipid-based nanoparticles have great potential owing to their biocompatibility and low toxicity in ...

Researchers at the University of Toronto and its hospital partners have developed a method for co-delivering therapeutic RNA ...

Researchers at the University of Toronto and its hospital partners have developed a method for co-delivering therapeutic RNA ...

Investors have circled back to healthcare stocks this year, and they’re likely to stick around. If they came for the ...

When high levels of low-density lipoprotein cholesterol (LDL-C or bad cholesterol) are untreated for a long time, they lead ...

Small interfering RNA (siRNA) drugs are a class of therapeutic agents that silence specific genes associated with inherited diseases. However, siRNA drugs have challenges because siRNAs often ...

Scientists have learned how plants keep viruses from being passed to their offspring, a finding that could ensure healthier ...

Yong Qin (West China School of Pharmacy, Sichuan University). A small interfering RNA (siRNA) investigational therapy that inhibits a gene involved in lipoprotein metabolism has been shown in a ...

Lifordi Immunotherapeutics, Inc., a biotech company developing antibody-drug conjugates (ADCs) for the treatment of ...

Reporting in Nature, Kumar and colleagues have now developed a method to target small-interfering RNA (siRNA) to the CNS, providing a safe and non-invasive approach for the delivery of this new ...

The double-stranded RNA is processed by an RNase III family enzyme Dicer, resulting in the generation of an siRNA, a 21–23-nucleotide (nt) RNA duplex, composed of a 19-mer sequence with ...

Small interfering RNA (siRNA) drugs are a class of therapeutic agents that silence specific genes associated with inherited diseases. However, siRNA drugs have challenges because siRNAs often ...