PCR amplification was carried out with three primers, nt 7,576–7,595, 12,260–12,280 and 12,479–12,459, of mouse mtDNA. Mutant ΔmtDNA4696 and wild-type mtDNA gave 210 bp and 220 bp fragments ...

PCR-based methods to detect mtDNA deletions in the clinical context seem preferable, as they are quick, inexpensive, require only very small amounts of biopsy material, are tolerant of poor sample ...

The other approach analyzes mitochondrial DNA, or mtDNA. Because mtDNA tends to survive long after nuclear DNA has disintegrated, this approach is useful in identifying the remains of persons who ...

Expand long PCR was used to investigate mtDNA deletion in soleus muscle and a sequencing method was used to confirm the mtDNA deletion break point. Results: Our results did not show any mtDNA deletion ...

Previous and on-going projects in this area include the mtDNA study of an ancient Italian population, the development of new PCR-based method to avoid false sex identification, DNA identification of ...