miRNAs are transcribed from a gene and processed by DCL1, SE and HYL1 into an RNA duplex (miRNA/miRNA*). The duplex is methylated by HEN and transported out of the nucleus by HST. The miRNA ...

(a) General diagram of the miRNA biogenesis pathway. (b) The major routes of cadmium exposure and its toxic impacts. AGO, Argonaute; Cd, cadmium; Exp5, Exportin 5; miRNA, microRNA; Ran/GTP ...

Nobel Prize in Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in ...

(3) There are many steps at which the biogenesis of different small RNA substrates can be regulated by trans-acting factors. Figure 1. Complexity of small RNA processing and loading pathways. This ...

Pablo Manavella has been appointed the next Editor-in-Chief of The Plant Cell, a leading high-impact society journal ...

Two scientists have been award the 2024 Nobel Prize in Physiology or Medicine for their discovery of microRNA. Victor Ambros, professor of molecular medicine at the University of Massachusetts ...

Biogenesis of America, a Miami wellness clinic fueled by a cocaine-addicted biochemist who introduced himself as "Dr. T," outed some of the nation's biggest stars as PED users; still others have ...

Promiscuous splicing-derived hairpins are dominant substrates of tailing-mediated defense of miRNA biogenesis in mammals. Cell Reports 42. Shang R, Lee S, Senavirathne G and Lai EC (2023). microRNAs ...