Yeast Yra1 and its metazoan orthologues ... RNA-binding protein Pab1 may jointly package mRNAs into an exportable configuration. After pre-mRNA processing, mRNPs would interact with NPCs, perhaps ...
Then, the mRNA is translated into protein within a structure called ... Previous research in yeast showed that when translation slows down, only one tRNA is left in the ribosome, in the P site.
RNA breaks destined for repair are inflicted by sequence-specific or structure-specific endoribonucleases during physiological RNA processing (e.g. tRNA splicing; kinetoplast mRNA editing ... tRNA ...
In eukaryotic cells, mRNA decay is catalyzed by two major pathways ... regulate the activities of Dis3 and Rrp6 on a variety of substrates. Structure of the yeast 12-subunit nuclear exosome We ...