Our research interests are in the areas of structure determination of biological nano-machines by electron cryo-microscopy (cryo-EM) techniques and computer reconstruction, and the use of structures ...

The Wang Lab first uses electron cryo-microscopy (Cryo-EM) to determine the structural architecture of DNA-bound ER-alpha, SRC-3, and a secondary coactivator (p300) complex. This work provides a ...

Our laboratory is dedicated to understanding the consequences ... McLaughlan S, Topisirovic I, Wang Z, Wang Z, Zhao Y, Wildes D, Aggen JB, Singh M, Gill AL, Smith JAM, Rosen N. Selective inhibitors of ...