Atherosclerosis, a disease characterized by the accumulation of lipids and inflammatory cells in the arterial wall, is a significant cause of cardiovascular events.

The etiology is unknown, but its pathogenesis involves an activated immune system, abnormal vascular endothelium, and an exaggerated production of fibroblasts that results in abnormal collagen ...

Fibroblast growth factors (FGFs ... FGFR agonists may be useful alternatives to FGF in the treatment of ischemic vascular disease. Clinical studies with FGF and other angiogenic molecules have ...

"We know that during the remodeling process fibroblasts are activated," said Cheng Hong, MD, Ph.D., pulmonary vascular medicine specialist at the First Affiliated Hospital of Guangzhou Medical ...

fibroblasts, neurons and glia. They regulate blood flow and provide vital support for brain development and neuronal function. Defective neuro–vascular function is associated with a variety of ...

F-FAPI PET -- can detect the first signs of tissue remodeling in patients with pulmonary arterial hypertension (PAH), providing physicians with an early marker for disease progression. This approach ...