A team of researchers from the Keck School of Medicine of USC has unlocked the details of a cellular pathway that triggers ...

Background Early-life inflammation has long been recognised as a key pathophysiological process in the evolution of cystic ...

Akeso, Inc. (9926. HK) ("Akeso" or the "Company") is pleased to announce the acceptance of its Investigational New Drug (IND) application by the China National Medical Products Administration (NMPA) ...

Eliminated the link between adipose tissue inflammation induced by LDL, or other metabolic and microbial inflammatory triggers, with several risk factors for type 2 diabetes and cardiovascular ...

Olive oil bioactives, including MUFAs, polyphenols, and triterpenoids, modulate gene expression linked to insulin sensitivity ...

Targeting JAKs and TYK2 In recent years, small-molecule oral treatments targeting Janus kinases (JAKs) and tyrosine kinase 2 (TYK2 ... cytokine pathways, reducing inflammation — and, as a ...

These novel inhibitors have also been shown to modulate the IL-4/IL-13 pathway and decrease type 2 inflammation in vivo, without degrading the STAT6 protein. DeepCure used its proprietary ...

thus demonstrating the presence of eosinophil- and type 2 effector-independent pathways of GZMK-mediated airway inflammation. CD8+ T-cells exhibit disease-promoting and disease-regulating ...

The following is a summary of “Role of glucocorticoid receptor expression in Chronic Chagas Cardiomyopathy: implications for ...

The submitted indications are for add-on maintenance treatment of asthma in adult and adolescent patients aged 12 years and older with type 2 inflammation characterised by an eosinophilic phenotype ...