The tissue adjacent to a tumor behaves differently than areas farther away: The tumor's cancerous cells influence their surroundings, blocking the body's immune defenses and creating a sort of haven ...

An immuno-oncology targeting panel accurately characterized tumor-resident immune cells and located pathologically and clinically relevant tumor microenvironment features. Cancer development and ...

The present study aimed to develop an ex vivo model that could mimic the pre-metastatic tumor microenvironment, incorporating ...

in the tumor microenvironment (TME). This discovery provides new insights into immune cell metabolism within tumors and ...

Our multidisciplinary approach spans areas such as tumor progression and metastasis, tumor microenvironment ... MD Craig Thompson studies molecular signaling pathways that regulate nutrient uptake and ...

Conversely, entosis also promotes the development of aneuploidy and allows engulfing cells to scavenge nutrients. These activities may promote tumor progression in the long term. This dual nature of ...

"We are presenting a treatment that might help a wide range of patients, since it focuses on the tumor microenvironment and not on the cancer cells themselves" We then wanted to see whether the ...