This model combined knowledge of tubulin biochemistry and spindle-microtubule polarity (polarity is indicated with plus and minus signs) and results indicating poleward flux. It predicted poleward ...

Mitotic spindles are dynamic, self-organizing ... we have reconstituted spindle-like structures assembled from a minimal set of purified proteins including tubulin and MAP65, a microtubule ...

Cell division is essential to the propagation of life. During cell division, mitotic spindles segregate duplicated chromosomes with high fidelity. Spindle structure depends on the proper polar ...

The five phases of mitosis and cell division tightly coordinate the movements of hundreds of proteins. How did early biologists unravel this complex dance of chromosomes? The most obvious ...

TTFs interfere with charged molecules involved in cell division. During mitosis, tubulin proteins assemble into spindle fibers that pull chromosomes into two separate cells. Alternating electrical ...

The sub-clades that were most closely related to animal and fungal tubulins included those expressed during flagellate differentiation, which represented the majority of cytoplasmic tubulin proteins ...

The sequence of amino acids in the chain determines how the chain will fold up to make the protein, so different proteins have different three-dimensional shapes. The three-dimensional shape of a ...