Circadian rhythms are endogenous time-keeping mechanisms that regulate physiological processes in response to external ...

A new paper from MUSC Hollings Cancer Center researchers is helping to reveal the "rules" for engineering chimeric antigen receptor (CAR) Tregs. Tregs, or T-regulatory cells, have shown promise in ...

LUND, SE / ACCESS Newswire / March 20, 2025 /BioInvent International AB ("BioInvent") (Nasdaq Stockholm:BINV), a biotech ...

Tumor tissue and ascites from patients with ovarian cancer contain high levels of cells with all the hallmarks of regulatory T cells. These cells migrate into the tumor microenvironment in a ...

On the one hand, circadian rhythm disorder contributes to tumor growth and metastasis by influencing the dysregulation of gene expression affecting the tumor itself. On the other hand, circadian ...

Reduced Treg function contributes to autoimmune diseases including diabetes, whereas increased numbers aggravate tumor and pathogen immunopathology 1. Thus, understanding differentiation pathways ...

In the arthritic environment, Treg cells exhibit altered metabolic ... including inflammation in other organs, infections, ...

an area of therapeutics development that is viewed as being at the forefront of extending the role of cell therapy beyond cancer. As their name suggests, Treg cells play a key role in controlling ...

The complete receptor is usually found on regulatory T (Treg) cells ... which await instructions before seeking out cancer cells. MDNA109 is an engineered version of IL-2 that binds up to 1,000 ...

SAN DIEGO and SUZHOU, China, March 13, 2025 (GLOBE NEWSWIRE) -- Adagene Inc. (“Adagene”) (Nasdaq: ADAG), a company transforming the discovery and development of novel antibody-based therapies, today ...

LUND, SE / ACCESS Newswire / March 20, 2025 / BioInvent International AB ("BioInvent") (Nasdaq Stockholm:BINV), a biotech company focused on the discovery and development of novel and first-in-class i ...