While we have some understanding of how Tregs modulate Th17, Th1 and Th2 cells, the precise molecular mechanisms require delineation. Equally important will be the dissection of the pathways that ...
[134] Th17 cells develop in response to the ... and that the reduced activity of Tregs and the unbalanced Th1:Th2 ratio observed in human endocrine autoimmunity occur at the site of regional ...
For instance, Th1 needs IL-12, Th2 needs IL-4, Tregs need TGF-β1, and Th17 needs IL-6. > 95 % as determined by SEC-HPLC. Image Credit: Sino Biological Inc. Cell proliferation assay using CTLL-2 ...