whereas the other daughter cell remains a stem cell with unlimited proliferative ability. Although most of the tissues in adult organisms maintain a constant size, the cells that make up these ...

This is something that's been widely appreciated but broadly overlooked when it comes to thinking about how tissues deal with ...

The tattoo was of the PIEZO mechanosensitive channel – a class of proteins that helps us sense pressure – and ... roles of PIEZO channels in stem cells of other tissues, especially when ...

Adult tissue-resident stem cells fuel renewal, repair, and remodeling of tissues to maintain their structure and function. Research in the Wickström lab aims to uncover how single stem cell behaviors ...

A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing ...

A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity, ...

Lizard experimentswere funded by NIH/NIGMS (grant number R01GM115444). Human tissue experiments were funded by USC Stem Cell ...

Our data suggest that strain is transferred over spatial scales from the tissue surface to nucleus interior ... Moreover, we have recently shown that substrate stretching and osmotic loading of single ...