Increased numbers of Th17 cells are found in inflamed tissue from patients with Crohn's disease and ulcerative colitis. IL-17A and IL-17F affect the pathogenesis of Crohn's disease and ulcerative ...

The study led by teams at The University of Manchester and National Institutes of Health in the USA, revealed that a specific type of immune cell, the Th17 cell, can be stimulated when you chew. The ...

could lead to the development of new therapies for inflammatory bowel diseases such as ulcerative colitis or Crohn's disease in the future, in addition to its importance for the treatment of PSC.

is an important step towards a better understanding of the role of Th17 effector cytokines and their impact on the development and maintenance of colitis. The authors propose that dual blockade of ...