Biochimica et Biophysica Acta 1788, 779–789 (2009). Juliano, R. L. Signal transduction by cell adhesion receptors and the cytoskeleton: Functions of integrins, cadherins, selectins, and ...
Cys-loop receptors are ligand-gated ion channels with two domains connected by a short linker. The top domain is located extracellularly, while the bottom domain sits in the cell membrane.