A new research paper was published in Oncotarget's Volume 15 on August 5, 2024, entitled, "Chemical complementarity of tumor ...

T cell therapies, which use genetically-engineered T cells of the human immune system as therapeutics, are revolutionizing ...

Successfully re-creating a T-cell receptor signaling pathway independent of the cell itself provides novel insights into how protein signaling works in a complex cellular process. with the Breaking ...

Research identifies cross-reactive T cells targeting both SARS-CoV-2 and human SNX8 protein, providing insights into the ...

T cells are white blood cells that are ... rearrangements that facilitate NCK recruitment to the T-cell receptor and downstream signaling. Here, the authors show that there is a pretumorigenic ...

The first Gordon Research Conference on `Signalling by Adhesion Receptors', which took place ... it cooperates with the transcription factor T-cell factor/lymphoid-enhancer factor (TCF/Lef ...

A protein called Meteorin-like (METRNL) in the tumor microenvironment saps energy from T cells, thereby severely limiting ...

“Our goal was to combine some of the advantages of the CAR format with those of the natural T cell receptor on T cells, supplemented with additional signaling boosters, so that they could fight ...

The long-lasting CAR T cells generated by the therapy could be restimulated by readministering CAR-E, the authors said. This ...

To produce the cells, called Co-STAR (Co-stimulatory Synthetic T-cell receptor and Antigen Receptor) cells, the researchers combined genetic components of four types of cells that the body ...

When T cells try to eliminate a tumor ... called E2F, that it is dependent on signaling by a receptor called PPAR delta, and that modulating these factors downstream can block the effects of METRNL.

Using genetic engineering techniques, investigators designed a novel type of cell to recognize and fight cancer. Using genetic engineering techniques, investigators at the Johns Hopkins Kimmel ...