The wide adoption of genetic engineering techniques in the late 1990’s played an important role in demonstrating the complexity and importance of communication between stromal cells and immune ...
The targeted epigenetic repression of a β 2-microglobulin super-enhancer downregulates the expression of human leucocyte antigens on mesenchymal stromal cells, making the cells suitable for ...
Stromal cell therapy is a promising frontier in lupus research, especially for people whose lupus doesn’t respond to other treatments (called refractory lupus). We were the first lupus organization in ...
A recent study offering a comprehensive view of the genome and transcriptome of gastrointestinal stromal tumors (GISTs) has ...
Some patients being treated with immune checkpoint inhibitors, a type of cancer immunotherapy, develop a dangerous form of heart inflammation called myocarditis. Researchers have now uncovered the ...
What are germ cell and sex cord stromal cells? Germ cells and sex cord stromal cells form when a fetus (baby) is developing. A fetus is made from a sperm cell and an egg cell. Germ cell tumors (GCTs) ...
Nature. 2016;530(7591):434-440 ... Sirpilla O, et al. Mesenchymal stromal cells with chimaeric antigen receptors for enhanced immunosuppression. Nat Biomed Eng. 2024;8(4):443-460. 20. Fransson M, et ...
A team led by Prof. Wang Chao and Prof. Huang Chengdong from the University of Science and Technology of China (USTC) of the ...
Stromal Cell Tumors This is the rarest type of ovarian cancer ... Ovarian cancer presents a unique challenge due to its silent nature. However, identifying the warning signs, seeking timely medical ...
Skeletal stem cells have been isolated from various tissues, including periosteum and bone marrow, where they exhibit key functions in bone biology and hematopoiesis, respectively. The role of ...
In a recent study published in Nature, researchers investigate the spatial organization of cancer cells and the tumor microenvironment by analyzing over one hundred tumor sections across six types of ...
In an example of stromal or connective tissue cells ... More information: Wenpin Hou et al, Assessing GPT-4 for cell type annotation in single-cell RNA-seq analysis, Nature Methods (2024). DOI: ...