Hematopoietic progenitor kinase 1 (HPK1), a member of the Ste20 serine/threonine kinases family, negatively regulates T cell function and is ...

The most often studied kinases are protein kinases, which are generally subdivided into tyrosine, and serine/threonine-directed kinases. As such, kinases are key signal transduction molecules relevant ...

Cisbio's HTRF® KinEASE™ assay for screening serine/threonine kinases now extends to tyrosine kinases (TK). The assay, developed in partnership with Millipore, uses a unique substrate containing ...

Cyclin-dependent kinase 5, a serine/threonine kinase, contributes to neurodegeneration in Parkinson's disease. This kinase is now shown to phosphorylate peroxiredoxin-2, inactivating it ...

Genzyme Corp. (Sanofi Genzyme) has identified receptor-interacting serine/threonine-protein kinase 1 (RIPK1; RIP-1) inhibitors reported to be useful for the treatment of Alzheimer’s disease, multiple ...