More information: Cherrelle Dacon et al, Protective antibodies target cryptic epitope unmasked by cleavage of malaria sporozoite protein, Science (2025). DOI: 10.1126/science.adr0510 ...

The circumsporozoite protein (CSP) has a key role in several stages of the Plasmodium life cycle, including the development of the sporozoite form of the parasite and its entry into the salivary ...

"The discovery of a new target on the sporozoite surface [the life stage ... one is to try and develop this as a new vaccine or make the protein as a therapeutic [a monoclonal antibody]," she ...