The Hedgehog (Hh) pathway plays central roles in animal development and stem-cell function. Defects in Hh signalling ... encoded by a tumour suppressor gene, and Smoothened (Smo), encoded by ...

As such, they're involved in dictating the skeletal pattern of tetrapods and do so by helping to control proteins created by ...

They used an altered form of cold virus to deliver what they have named the "Sonic hedgehog" gene (after a video-game character), which plays a central role in hair follicle development.

Please verify your email address. Shadow the Hedgehog, a fan-favorite, features in a number of Sonic the Hedgehog games since Sonic Adventure 2. Shadow is playable in various titles like Sonic '06 ...

Silver debuted in Sonic the Hedgehog 2006 and was, alongside Sonic and Shadow, a main playable character with his own story campaign. Silver had a unique skill set but controlled much slower than ...

Following is a transcript of the video. Narrator: Sonic the Hedgehog famously went through a drastic design change for his first Hollywood film. Fans were so upset at this [screaming] that the ...

Sega has posted a short video via social media giving fans a tantalising look at an upcoming character skin available via the Sonic X Shadow Generations Digital Deluxe Edition. As previously ...

It's been 30 years since one of gaming's most-loved characters, Sonic the Hedgehog, first raced across our TV screens. In the early 1990s it was Nintendo and its moustached mascot Mario who ...

Sonic the Hedgehog 3 is on the way, and there are already exciting updates about the blue speedster's latest adventure. The ...

It's a huge privilege, therefore, to be able to introduce the below sketches from Sonic Team's Kazuyuki Hoshino, from the development of the Shadow the Hedgehog game. Before this, Hoshino worked ...

Sonic the Hedgehog — the blue dude with the most 'tude — first sprinted onto the Mega Drive in 1991, when Sega finally presented a credible challenger for the platforming throne that Mario had ...

All the latest news and features on Sonic The Hedgehog video games, movies and TV shows. Sonic is a video game character created in 1991 for the SEGA gaming console. He has gone on to appear in ...