One explanation for phasing is that only one secondary siRNA is made per round. Possible routes for such synthesis are self-termination of RdRP activity, or more processive RdRP activity coupled ...

RNA-dependent RNA polymerase (RdRp), is essential in RNA replication within the life cycle of the severe acute respiratory coronavirus-2 (SARS-CoV-2), causing the deadly respiratory-induced sickness ...

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Yong Qin (West China School of Pharmacy, Sichuan University). A small interfering RNA (siRNA) investigational therapy that inhibits a gene involved in lipoprotein metabolism has been shown in a ...