Novel regulatory pathways linking fat mass ... fully humanized monoclonal antibody acts like OPG to inhibit RANKL/RANK signaling and decrease bone resorption. A recombinant human OPG–Fc fusion ...

It is hoped that a catalogue of most disease-associated DNA variants for the best-studied complex conditions, such as cardiovascular disease, diabetes and autism, will be available in the next decade.

A molecular signalling pathway called ... Through RANK–RANKL signalling, sex and pregnancy hormones seem to trigger a rewiring of the immune system, breast, bone and intestine to maintain ...