T cell therapy has achieved notable success in treating blood cancers. However, it has been largely ineffective against solid ...

New research from St. Jude Children's Research Hospital and colleagues found that disrupting Asxl1, a gene in T cells, ...

A new cell therapy, targeting CD7 in leukemia cells, gives a potentially effective treatment for patients with T-cell acute ...

Analyzing the genetics of patients that responded well to checkpoint blockade revealed mutations in the gene Asxl1 in immune T cells. Disrupting the Asxl1 gene in T cells enhanced response to immune ...

T cells are our first line of defense against cancer, but the battle tends to exhaust them. Now, scientists have found a way to give them extra “batteries” to keep them fighting longer ...

Cells of the innate system respond rapidly to molecular patterns shared by a broad array of pathogens. Meanwhile, the adaptive system, consisting of T and B cells, responds more slowly, targeting ...

T cells are white blood cells that are important for adaptive immunity. They have unique cell surface receptors that are generated by randomly assorting genes. These receptors allow T cells to ...

The well-established existence of sex differences in immune responses, including immune responses driven by T cells, cuts ...

CAR T-cell therapy is a type of immunotherapy. CAR stands for chimeric antigen receptor. You might also hear it called a type of adoptive cell transfer. CAR T-cell therapy is a very complex and ...

These cells deal with microbes and repair tissue damage. Two main sub-types of immune cells are T cells and macrophages. T cells are designed to recognise the molecular signatures of particular ...

Oct. 9, 2024 — Researchers have developed a groundbreaking cell culture platform that enables the formation of two distinct but interconnected vascular networks. Their breakthrough holds ...

CD8-positive T cells are a critical subpopulation of MHC class I-restricted T cell and are mediators of adaptive immunity. They include cytotoxic T cells, which are important for killing cancerous ...