What's the difference between mRNA and pre-mRNA? It's all about splicing of introns. See how one RNA sequence can exist in nearly 40,000 different forms. Next, the snRNPs U2 and U4/U6 appear to ...

Splicing produces a mature messenger RNA molecule that is then translated into a protein. Introns are also referred to as intervening sequences.

Shown is the splicing pathway. The pre-messenger RNA (pre-mRNA) has exons (blue) and introns (pink). The spliceosome (not shown) was known to catalyze two chemical reactions (black arrows ...

As its name suggests, splicing involves snipping out certain sequences in the RNA called introns, with the remaining sequences (exons) reconnected to one another to form the functional molecule.

Interestingly, these elements reside in introns, sections of DNA flanking ... resulting in the removal of an entire exon ...

Researchers unveil the inner mechanisms of the most intricate and complex molecular machine in human biology. Scientists at the Centre (CRG) in Barcelona have developed the first comprehensive ...

“The spliceosome is the complex molecular machinery that sequentially assembles on eukaryotic messenger RNA precursors to remove introns (pre-mRNA splicing), a physiologically regulated process ...

"There is a lot of evidence that the RNA parts of the spliceosome, the snRNAs, are closely related to Group II introns." Because the chemical mechanism for splicing is very similar between the ...

This important manuscript provides insights into the competition between Splicing Factor 1 (SF1) and Quaking (QKI) for binding at the ACUAA branch point sequence in a model intron, regulating exon ...