So, the fact that it's working through two different mechanisms on this oncogene may explain why it's so effective in tumors ...

A pancreatic cancer drug extends symptom-free survival in preclinical medulloblastoma models, targeting MYC oncogene in Group ...

So, the fact that it's working through two different mechanisms on this oncogene may explain why it's so effective in tumors ...

For Lucas Farnung, there is no question more fascinating than how a single fertilized egg develops into a fully-functioning ...

Eukaryotes transcribe much of their genomes, but little is known about the fidelity of transcriptional initiation by RNA polymerase II in vivo.I suggest that ∼ 90% of Pol II initiation events in ...

Our studies of the central role of the RNA polymerase II (Pol2) carboxyl-terminal domain (CTD) and CTD phosphorylation in directing the capping enzymes to nascent pre-mRNAs helped establish the ...

The virus uses its own RNA copying machine, called a polymerase, to make duplicates of RNA inside the vesicles. Some of the copies are utilized to make more viral proteins, such as the spike.

Our mission is to elucidate fundamental mechanisms that control the elongation phase of transcription by RNA polymerase II (Pol II) in normal and disease states. We are particularly interested in ...

Applied DNA Sciences, Inc. (NASDAQ:APDN) (Applied DNA), a leader in PCR-based DNA technologies, today announced that the U.S. Defense Logistics Agency (DLA) exercised the first one-year option period ...

The goal of my research is to understand the mechanisms and structures of enzymes that perform and regulate essential nucleic acid transactions. My research integrates diverse experimental approaches ...

Inc. ("Spindle"), the development and sale of a proprietary RNA polymerase ("RNAP") for use in the production of mRNA therapeutics; (ii) the detection of DNA and RNA in molecular diagnostics and ...