In addition to their role in nucleic acids, purines are involved in various cellular metabolic processes. Purine nucleotides, such as ATP and GTP, serve as energy carriers and regulators of cellular ...

Uric acid is the final product of purine metabolism. The two types of purines are: Once purines are formed or enter the body, they are metabolized (processed) into uric acid, a waste product ...

Genetic variations affecting enzymes and transporters involved in purine metabolism and UA excretion have been identified, paving the way for personalized treatment strategies. Advances in ...

They soon discovered, from observing the role of purines in nucleic acid metabolism, that bacterial cells require certain purines to make DNA. Hitchings hypothesized that by preventing those purines ...