Jiangsu Vcare Pharmatech Co. Ltd. has created new proteolysis targeting chimera (PROTAC) compounds comprising an E3 ubiquitin ligase-binding moiety covalently linked to estrogen receptor α ...

Fill out the form below and we'll send your colleague an invitation to the "Expanding the PROTACtable Genome Universe of E3 Ligases" event. Proteolysis-targeting chimera (PROTAC) and other targeted ...

This still creates the proximity required for the E3 enzyme to interact with the target protein but means that each PROTAC ...

Arvinas utilizes PROTAC technology to develop protein degraders with vepdegestrant as a lead drug candidate in Phase 3 ...

It’s been five years since the last official E3, and Xbox now has the honor of having held what many are calling an “E3-caliber showcase” this past weekend. It was a nonstop stream of game ...

Almost a year after announcing its return, the Entertainment Software Association announced today to its members that this year's Electronic Entertainment Expo (E3), has been canceled, IGN can ...

A PROTAC is a heterobifunctional molecule that can bind both a target protein and an E3 ubiquitin ligase to facilitate the formation of a ternary complex, leading to ubiquitination and ultimate ...

Profacgen is pleased to announce its expanded offerings in the field of Proteolysis Targeting Chimeras (PROTACs). SHIRLEY, NEW YORK, UNITED STATES, June 26, 2024 /EINPresswire / -- Profacgen, a ...

It also offers PROTAC/molecular glue services, including protein preparation and ternary complex structure determination, screening for molecule glues and novel E3 ligase ligands, PROTAC ternary ...