Stanley Prusiner of the University of California, who first developed the theory of the prion as an infectious agent, received a Nobel Prize for his work in 1997. The cause of Creutzfeldt-Jakob ...

A system for the rapid amplification of misfolded prion oligomers provides new evidence supporting the prion hypothesis and may offer a powerful diagnostic tool. The prion hypothesis remains ...

These observations suggest that a diagnostic test for prion infections based on CSF or other non-brain tissues or excretia may be possible. Further studies will be required to demonstrate the ...