Investigation shows how bacterial adhesins contribute to colon cancer mutations, suggesting new avenues for therapeutic ...

A single enzyme fine-tunes red and yellow pigments in parrots’ polychromatic plumage, according to a new study. The findings reveal new insights into the molecular mechanisms underlying the evolution ...

TerraGen is also exploring the use of direct evolution of streptomycete polyketide enzymes to yield novel structures. Polyketides (e.g., erythromycin) are complex organic molecules synthesized by ...

A single enzyme fine-tunes red and yellow pigments in parrots' polychromatic plumage, according to a new study. The findings ...

Extensive strain screening has identified many useful polyketide derived compounds of both 'macrolide' and 'polyaromatic' type produced by bacteria. In order to understand the biosynthetic processes ...

The chemical mechanism underlying parrots’ vibrant plumage has been elucidated for the first time. The researchers behind the ...

Antonio Del Rio Flores will start as a Patten Faculty Fellow for CU Boulder's Department of Chemical and Biological Engineering in Spring 2026 (recruiting graduate students for Fall 2025). He earned a ...

The work of his group on giant multifunctional enzymes involved in fatty acid synthesis offer first mechanistic insights into substrate shuttling and delivery in such megasynthases, with direct ...

Enzymes are extraordinary biocatalysts –they are the machinery within cell factories crafted by Nature over aeons of evolution. The aims of my research are focused upon using techniques in synthetic ...

Jim Staunton, Peter Leadlay, Tu Youyou and my daughter Esther. I was blown away when Jim Staunton showed a cartoon of the beautiful multifunctional enzymatic machinery that make up polyketide ...

1.AmagaiK., Ikeda H., Hashimoto J., Kozone I., Izumikawa M., Kudo F., Eguchi T., Nakamura T., Osada H., Takahashi S., and Kazuo Shin-ya K.: "Identification of gene ...