In the weeks before her death, my wife, Diane Shader Smith, and I sought out and obtained an innovative yet underused treatment for antibiotic-resistant bacteria known as phage therapy.

Eligo Bioscience has engineered a phage-derived vector to base edit Escherichia coli while they are colonizing the mouse gut.

Recognizing the specificity of phage therapy and its ability to spare beneficial bacteria from adverse effects, we focused our research on phage-derived lytic enzymes." The team initiated their ...

A vector can be represented by a line segment labelled with an arrow. A vector between two points A and B is described as: \(\overrightarrow{AB}\), \(\mathbf{a}\) or \(\underline{a}\). The vector ...

like hybridoma screening or high throughput platforms like yeast or phage display. The process is followed by computationally guided mutagenesis or evolution of the antibody sequence (hit to lead ...

A vector can be represented by a line segment labelled with an arrow. A vector between two points A and B is described as: \(\overrightarrow{AB}\), \(\mathbf{a}\) or \(\underline{a}\). The vector ...

If you're a professional designer or illustrator, there's no beating the industry standard vector editing software. Adobe Illustrator is available as a standalone app, or as part of the Creative ...

The findings are valuable however, the study is incomplete as the primary claims related to hypoxia adaptation need additional experimental support and data presentation requires more clarity. The ...

June 10, 2024. doi: 10.1038/s41551-024-01227-1 Examination of the mechanisms underlying phage-bacteria warfare has led to the identification of effectors crucial to DNA cloning, editing ...

This valuable study explores a new strategy of lysin-derived antimicrobial peptide-primed screening to find peptidoglycan hydrolases from bacterial proteomes. Using this strategy, the authors ...