Wegener's granulomatosis, microscopic polyangiitis (MPA), Churg–Strauss syndrome, and primary pauci-immune crescentic ... detect the presence of vasculitis-associated ANCA is by using ...

Kain et al. suggest that molecular mimicry is also the fundamental mechanism in development of pauci-immune FNGN in patients with ANCA. However, the antigen involved is not proteinase 3 or ...

So the diagnosis was a crescentic pauci-immune ANCA-associated vasculitis and given the PR3 positivity and C-ANCA positivity, very likely granulomatosis with polyangiitis or GPA. So let's take ...

The pathology of WG/GPA is characteristically described as a granulomatous necrotizing inflammation and pauci-immune vasculitis of ... cytoplasm antibody (ANCA), although not all cases may be ...