a better approach would be to develop a therapeutic or supplement that will delay the onset of diseases by preventing the underlying molecular defects that cause them." The nucleolus may hold the key.

“Neurodegenerative diseases affect millions of people worldwide ... pathways that regulate proteostasis. For instance, the nucleolus not only acts as a protein quality control hub but also ...

Nuclei (white, Hoechst) and nucleolus (cyan, a-Fibrillarin ... Individual muscles also have different susceptibilities to diseases like muscular dystrophy, muscle myopathies, and rhabdomyosarcoma.