The antibody has a 'high' affinity and specificity towards the myeloid checkpoint leukocyte immunoglobulin like receptor B2 (LILRB2). "Immune-Onc doses first subject in trial of IO-108 for HCC ...

Triggering receptors expressed on myeloid cells (TREMs) are a cell surface receptor family found on granulocytes, monocytes, macrophages, and dendritic cells—as well as other myeloid cells in general.

More information: Stefanie Weiss et al, Atovaquone and selinexor as a novel combination treatment option in acute myeloid ...

Myeloid cells invade tumors in response to diverse inflammatory stimuli produced by the tumor. Invading myeloid cells differentiate into a type of macrophage that promotes tumor angiogenesis ...

To define routes and mechanisms of leukocyte infiltration into the peritoneum during peritonitis a multiscale imaging approach will be employed to analyse the temporo-spatial dynamics of the ...

Sanofi to acquire Dren Bio’s bispecific myeloid cell engager for deep B-cell depletion, broadening immunology pipeline Dren Bio deep B-cell depleter program has the potential to reset the immune ...

(3) The effect of LBH589 on directly isolated myeloid DCs was also tested by allogeneic ... anti-CD86, anti-human leukocyte antigen (HLA)-ABC, and anti-HLA-DR monoclonal antibodies (BD Pharmingen).