AD and associated neuropathologies have also been reported in individuals with trisomy 21 mosaicism. A man with 10 percent mosaicism in his peripheral lymphocytes, died at age 64 with severe AD ...

This paper describes a family with 3 affected sibs with regular trisomy 21 Down syndrome. The condition seems to be transmitted from a phenotypically normal mother in whom G-trisomy mosaicism was ...