One target for such inhibition, the p38 mitogen-activated protein kinase (MAPK) signaling cascade, has a role in inflammation by mediating the cellular response to stress, pathogens, and cytokines.

Recent data suggests a direct link between the surface estrogen receptor and the mitogen-activated protein (MAP) kinase signaling cascade ... Raf and mitogen-activated protein kinase kinase ...

(Most of these details come from Fred Beckey’s seminal “Cascade Alpine Guide: Climbing and High Routes, Vol. 2: Stevens Pass to Rainy Pass,” one of the Bibles of the climbing set. Full of ...

The region forms part of the Cascade Range, named for its innumerable waterfalls. The range extends from British Columbia to northern California. A geological theory proposes that the mountains ...

Tako-Tsubo cardiomyopathy is characterized by transient left ventricular dysfunction after a stressful emotional or physical episode. Despite a sometimes severely impaired left ventricular ...

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Polo-like kinase 1 (PLK1) promotes CENP-A replenishment by initiating a cascade of chemical and conformational changes in the refilling machinery. The findings advance understanding of centromere ...

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Conclusion PI3K/AKT signalling is activated in TTC. This activated cell survival cascade might protect cardiomyocytes from cell death and also contribute to rapid regeneration in TTC. Tako-Tsubo ...