One target for such inhibition, the p38 mitogen-activated protein kinase (MAPK) signaling cascade, has a role in inflammation by mediating the cellular response to stress, pathogens, and cytokines.

Thalassemia is a genetic disorder characterized by reduced or absent synthesis of the beta chains of hemoglobin, leading to ...

Over the past twenty years, intensive research has enabled us to identify components of specific signalling pathways downstream of an array of adhesion and growth-factor receptors. The first ...

The region forms part of the Cascade Range, named for its innumerable waterfalls. The range extends from British Columbia to northern California. A geological theory proposes that the mountains ...

(Most of these details come from Fred Beckey’s seminal “Cascade Alpine Guide: Climbing and High Routes, Vol. 2: Stevens Pass to Rainy Pass,” one of the Bibles of the climbing set. Full of ...

In this interview, AZoMaterials speaks with Ms. Saba Adil about why Metrohm's Ion Chromatography System is key to achieving the quality and precision required for the National Center for Water ...

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A total of 19 patients were screened for enrolment in this study between March 2005 and July 2007. All patients presented with symptoms of an acute coronary syndrome, including acute onset of ...

We include products we think are useful for our readers. If you buy through links on this page, we may earn a small commission. Here’s our process. For athletes and active adults who don’t eat ...

They compared siNRA SQ61K therapy efficacy to the mitogen-activated protein kinase inhibitor (MEKi ... a single dosage of siRNA induces an apoptotic cascade, unlike treatment with an MEK inhibitor.