Using a version of the enzyme which localizes to lysosomes and a chemical known to puncture the lysosomal membrane, he was able to biotinylate all the proteins surrounding the damaged organelle. Tan ...
Using this tool, they established that after autophagosomes form, they fuse to the lysosomal membrane to form a structure known as the autolysosome (Figure 1). Then, depending on the stimuli that ...
Any proteins that are destined for a lysosome are delivered ... a molecular assembly line in which membrane proteins undergo extensive post-translational modification. Many Golgi reactions involve ...
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