has been shown to counteract the effects of inflammatory stimuli like lipopolysaccharides (LPS) that induce endothelial hyperpermeability. Research demonstrated that activating ATF6 can prevent ...

This study aimed to investigate the effects and potential mechanisms of LHQK on endothelial protection in LPS-induced ALI/ARDS in vivo and in LPS-induced human pulmonary microvascular endothelial ...

without interfering with mitochondrial electron transport or cellular bioenergetics. The ability of paroxetine to improve hyperglycemic endothelial cell injury was unique among serotonin reuptake ...

Studies have shown that mutations in SLC4A11 can lead to mitochondrial dysfunction and increased oxidative stress in corneal endothelial cells, contributing to the pathology of CHED. For instance ...

3 endothelial cells, we conducted cell-based screening to identify compounds that inhibit the mitochondrial ROS production induced by elevated extracellular glucose. We have tested a focused ...